Молекулярная и генетическая медицина

A Comprehensive Review of Chromosome 4q Deletion Syndrome

Abstract

Aida Parsa Sadat, Tahereh Taheri and Shahin Asadi*

Chromosome 4q deletion syndrome is a chromosomal disorder caused by the loss of a segment of the long arm of chromosome 4. It was first described in 1967 and is associated with symptoms in several organ systems. Some children with 4q deletion syndrome have psychiatric symptoms. These include aggression, hearing passive speech (verbal hallucinations), mood swings, and delusions. It should be noted that not all people with 4q deletion syndrome have these symptoms and the symptoms can vary greatly.