Ciro Manzo
Polymyalgia rheumatica (PMR) is considered the commonest rheumatic inflammatory disease in the elderly. The relationship between PMR and cancer is still complex. The possibility that PMR can represent a paraneoplastic syndrome has been more and more descripted. A lack of response to corticosteroid therapy is considered the principal element for looking for a paraneoplastic syndrome. Gastric gastrin-secreting tumor represents an uncommon gastric tumor, especially in the elderly. We describe the clinical case of a patient in which PMR associated with a mild macrocytic anemia was the key for diagnosis of a gastric gastrin-secreting tumor. Endoscopic removal of neoplastic polyps and an octreotide long-lasting therapy caused the prompt and permanent disappearance of PMR manifestations. According to our knowledge, it’s the first time that this association is descripted.
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