Журнал интервенционной и общей кардиологии

Advancements in Cardiac Care: The Role of Photodynamic Therapy

Abstract

Nicholas Teman*

Cardiovascular diseases remain a leading cause of mortality worldwide, urging the continual pursuit of innovative therapeutic strategies. Photodynamic Therapy (PDT) emerges as a promising technique in cardiac care, leveraging light activation of photosensitizing agents to induce localized cytotoxicity or modulate biological pathways. This abstract delves into recent advancements in PDT applications for cardiac conditions, highlighting its potential to revolutionize treatment paradigms. Firstly, we explore PDT's efficacy in treating atherosclerosis, a pivotal contributor to coronary artery disease. Preclinical studies demonstrate the capacity of PDT to selectively target atherosclerotic plaques, promoting plaque stabilization and regression while minimizing systemic side effects. Moreover, PDT's ability to modulate inflammatory responses within plaque microenvironments presents a multifaceted approach to combating atherosclerosis progression.