Журнал клинических респираторных заболеваний и ухода: открытый доступ

Advances in Pulmonary Hypertension: Exploring Pathophysiology, Diagnostic Strategies and Novel Therapeutic Approaches

Abstract

Mirouse Adrien

Pulmonary Hypertension (PH) is a complex and life-threatening condition characterized by elevated blood pressure in the pulmonary arteries, leading to increased strain on the heart and impaired blood flow to the lungs. Over the years, significant progress has been made in understanding the pathophysiology of PH, developing advanced diagnostic strategies and exploring novel therapeutic approaches. This article aims to delve into the recent advancements in these areas, shedding light on the evolving landscape of PH management. It affects the pulmonary vasculature, causing narrowing, stiffening and remodelling of the blood vessels. This increased pressure puts strain on the right side of the heart, leading to its enlargement and eventual heart failure if left untreated.