Журнал иммунобиологии

Advancing Chronic Wound Healing through Immune Modulation: Insights from Biomaterials and Nanomedicine

Abstract

Evelyn Chang

Chronic wounds represent a significant clinical challenge, characterized by impaired healing processes that prolong patient morbidity and healthcare costs. Traditional approaches to wound management often focus on controlling infection and promoting tissue regeneration. However, emerging research has highlighted the critical role of immune modulation in orchestrating wound healing dynamics. This review explores recent advancements in leveraging biomaterials and nanomedicine to modulate the immune system effectively towards promoting functional chronic wound healing. Key insights from experimental and clinical studies are synthesized to illustrate the potential of these innovative approaches in improving patient outcomes and advancing wound care practices.