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Медицинская химия

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An Atom-economic and Facile Synthesis of Novel 4-Imino-3-phenyl-2-substitutedphenyl-5-tolyl-2H,3H,5H[1,2,5]thiadiazolidine-1-oxide through 1,3-Dipolar Cycloaddition Reactions

Abstract

Vasudha Kaushal, Anjandeep Kaur and Baldev Singh

An atom economic and facile synthesis of novel thiadiazolidine-1-oxides has been achieved via using 1,3-dipolar cycloaddition reactions. The salient features of synthetic procedure are characterized by the good yields, high regio- and stereoselectivity, one-pot procedure, and operational simplicity. The regiochemistry and structures of the cycloadducts were determined by using various spectroscopic techniques (IR, 1H-NMR, ESI-MS) and elemental analyses data.

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