Журнал клинической и медицинской геномики

Assessing Protein Mutation Effects in Cancer Genomics: Current Strategies and Future Prospects

Abstract

Marchi Allen

Understanding the functional impact of protein mutations is crucial for unraveling the complexity of cancer genomics and advancing personalized medicine. This research article comprehensively reviews current methodologies and emerging trends in assessing the effects of protein mutations in cancer. We discuss computational tools, experimental approaches, and integrative strategies that contribute to the prediction and validation of mutation effects. Additionally, we explore future directions aimed at enhancing the accuracy and clinical relevance of mutation assessment in cancer genomics.