Журнал биометрии и биостатистики

Big Data Science and Its Applications in Health and Medical Research: Challenges and Opportunities

Abstract

Yulan Liang and Arpad Kelemen

Recently, Big Data science has been a hot topic in the scientific, industrial and the business worlds. The healthcare and biomedical sciences have rapidly become data-intensive as investigators are generating and using large, complex, high dimensional, and diverse domain specific datasets. This paper provides a general survey of recent progress and advances in Big Data science, healthcare, and biomedical research. Big Data science impacts, important features, infrastructures, and basic and advanced analytical tools are presented in detail. Additionally, various challenges, debates, and opportunities inside this quickly emerging scientific field are explored. The human genome research, one of the most promising medical and health areas as an example and application of Big Data science, is discussed to demonstrate how the adaptive advanced computational analytical tools could be utilized for transforming millions of data points into predictions and diagnostics for precision medicine and personalized healthcare with better patient outcomes.