Журнал клинических случаев

Bladder Lymphoepithelioma-Like Carcinoma: Case Report and Literature Review

Abstract

Lai-Tiong F, Rustam F, Foahom Kamwa A, Chapuis H, Albouy A and Houédé N

Urinary lymphoepithelioma-like carcinoma is a rare tumour. These tumours are classified according to lymphoepithelioma component as pure (100%), predominant (≥50%) or focal (<50%). We present here an original case of a 54 year-old man who was diagnosed with a LECL of the urinary bladder. The results of histological examination confirmed a high-grade T2 transitional cell carcinoma with LELC >50%. Neoadjuvant gemcitabine and platinium-based chemotherapy was carried out. The patient received four cycles with a good tolerance. After completed chemotherapy, the patient underwent a radical cystoprostatectomy with lymph nodes dissection and bricker urinary diversion. It’s difficult to define the optimal strategy, literature reporting only small series. Nevertheless, the benefits of chemotherapy is certain. The outcome is good in the pure and predominant forms and bad in focal subtypes.