Журнал клинических случаев

Cellular Neurothecoma: A Case Report of a 56-Year-Old Man

Abstract

Salma Jebli*, Basma El Khannoussi, S. El Aouni, N. Ammar, N. Rguieg, A. Jahid, F. Zouaidia, Z. Bernoussi and K. Znati

Cellular neurothecoma is a rare benign skin tumor, which must be distinguished from certain malignant tumors, in particular fibro-histiocytic plexiform cell tumors, clear cell sarcomas ... We report a new case of a 56-year-old man, who consulted for a skin lesion in the lumbar region, measuring approximately 2 cm in diameter. Histological examination showed a tumor proliferation located in the dermis and arriving at the superficial part of the hypodermis, made up of bundles of spindle cells and epithelioids with abundant eosinophilic cytoplasm, oval nucleus and fine chromatin. These bundles were separated by fibrous trabeculae isolating the tumor from the epidermis. The cells expressed CD10, CD99 and CD34 and were negative for PS100, GFAP, desmin, EMA, AML and STAT6. Thus, the diagnosis retained was that of a cellular neurothecoma.