Journal of Bioanalysis & Biomedicine

Characterization of Novel Biomarkers for Prostate Cancer Diagnosis Using Mass Spectrometry-based Proteomics

Abstract

Veronica Vicente

Prostate cancer remains one of the leading causes of cancer-related deaths among men, necessitating the development of more precise diagnostic tools. This study aimed to identify and characterize novel biomarkers for prostate cancer diagnosis using mass spectrometry-based proteomics. Serum samples from prostate cancer patients and healthy controls were analyzed, leading to the identification of several proteins differentially expressed between the two groups. These findings were validated using targeted proteomics, highlighting their potential utility in clinical diagnostics. Our results demonstrate the effectiveness of mass spectrometry-based proteomics in uncovering novel biomarkers, offering promise for improving prostate cancer diagnosis.