Ветеринарная наука и технологии

Comparative Study of Two Therapies Pharmacological Based a Ivermectin and Febendazol by Strongyles Control Intestinal in Thorougbreds Horses

Abstract

Sneiry Pérez-Álvarez, Keysamir Rojas-Mujica, Héctor Bello, Diana Villoria and Abelardo Morales

The aim of this study was to comparative of two therapies pharmacological based ivermectin and febendazole by Strongyles control intestinal in Thoroughbreds horses. Were study 110 horses all of 2 years old (55 Stallion and 55 Mares), in the Racetrack “La Rinconada” Caracas-Venezuela. A stool test was performed prior to treatment to each horse. Group 1: 50 horses were evaluated before treatment, using a stool test, then was given Ivermectin (0.2 mg/kg) 1% 7 ml, with reassessment intramuscularly coprological at 7 days. Group 2: 50 horses were evaluated before treatment, using a stool test, Fenbendazole was later administered (5 mg/kg) 18.8% oral paste 12 g. With reassessment coprological at 7 days. Group 3: 10 equines those not administered drug therapy, alone parasite burden was assessed using a fecal examination by Willis test. Anthelmintics effectiveness was conducted by counting fecal drug-treated group and the untreated control group. The results Group1 with Ivermectin 2.38 EPG showed pre-treatment and post treatment 7 days EPG 0.48. The group2 with Fenbendazole obtained 2.66 EPG and 7 days post treatment was obtained 0.06 EPG. Group 3 without medication present the following day 1.9 EPG value and then at 7 days 2 EPG. Comparing the effectiveness of both drug treatment and fenbendazole ivermectin antiparasitic indicate that fenbendazole base is more effective against the equine intestinal Strongylus, taking a percentage of 97% in comparison with specifically macrocyclic lactones which Ivermectin obtained a much lower drug efficacy throwing only 76%.