Журнал клинических случаев

Completely Disappear of Giant Lung Metastases of Pancreatic Cancer Treated with Gemcitabine and Oxaliplatin Chemotherapy: A Case Report

Abstract

Yu Yuan and Ren Cheng Sun

Pancreatic cancer is one of the most lethal cancers, most patients (80%) were diagnosed as inoperable advanced pancreatic cancer at the first time, and over 60% patients received operation relapsed within 2 years. Chemotherapy remains the mainly treatment for inoperable advanced or recurrent pancreatic cancer. Even though, gemcitabine and oxaliplatin was approved as a first-line therapy for advanced pancreatic cancer, their effect is unsatisfactory, especially for cases with distant metastases. In this paper, we report a case of lung metastases of pancreatic cancer showed complete response (CR) after received gemcitabine and oxaliplatin chemotherapy. This patient has a 9.5 cm × 9 cm × 7.5 cm size mass in right lung, three years after whipple procedure for pancreatic cancer. Then, the lung metastases disappeared completely, after 6 cycles of GEMOX. The result of this case report hints us GEMOX was a better choice for metastatic pancreatic cancer than other combination chemotherapy, especially for patients with distant metastasis to lung.