Журнал гипертонии: открытый доступ

Correlation of Systemic Arterial and Portal Venous Pressure in a Healthy Liver Animal Model

Abstract

Heyansh Kreiselukas*

In this study, we investigated the correlation between systemic arterial pressure (SAP) and portal venous pressure (PVP) using a healthy liver animal model. The experiment involved simultaneous measurements of SAP and PVP under baseline conditions and during controlled alterations in systemic and portal circulation parameters. Specifically, increases in SAP consistently corresponded to elevated PVP, highlighting the intricate interplay between systemic arterial perfusion and portal venous dynamics in maintaining hepatic hemodynamics. These results provide valuable insights into the physiological mechanisms governing liver blood flow regulation and underscore the potential implications for understanding and managing conditions such as portal hypertension and liver cirrhosis. Further exploration of these relationships could enhance our understanding of hepatic vascular physiology and inform therapeutic strategies aimed at optimizing liver perfusion in health and disease.