Arlet Georgina
Multidrug resistance proteins (MRPs) constitute a family of membrane-bound transporters that play a pivotal role in cellular detoxification and the disposition of endogenous and exogenous compounds. Their involvement in the efflux of various therapeutic agents has profound implications for pharmacokinetics, drug efficacy, and resistance development. This article aims to elucidate the intricate interplay between MRPs and their drug substrates, exploring the mechanisms underlying drug resistance and providing insights into potential therapeutic strategies.
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