Журнал молекулярной гистологии и медицинской физиологии

Detection of Synthetic Lethality Signaling in Human Cells

Abstract

Tomas Korski

Synthetic lethality is a promising concept in cancer research and targeted therapy development. This study focuses on the detection of synthetic lethality signaling in human cells, which involves identifying genetic interactions that render cancer cells vulnerable to specific therapeutic interventions. We employ advanced genomic and computational approaches to uncover these interactions and their underlying mechanisms. By elucidating synthetic lethality networks, this research contributes to the development of more effective and personalized cancer treatment strategies. Our findings shed light on the intricate interplay of genetic factors in cancer cell survival, offering new insights for precision medicine.