Журнал судебно-медицинских исследований

Determination of 3,4-methylenedioxymethamphetamine (MDMA) in Confiscated Tablets by High-Performance Liquid Chromatography (HPLC) with Diode Array Detector

Abstract

Natalia Biziak de Figueiredo, Érica Naomi Oiye, Matheus Manoel Teles de Menezes, José Fernando de Andrade, Maria Cristina Brunini Silva and Marcelo Firmino de Oliveira

Chromatographic analysis by the HPLC technique with Diode Array Detector was employed for MDMA determination. A mobile phase of methanol/water (90:10v/v) allowed a peak signal for MDMA in 16 minutes. Optimized spectrophotometric signal was obtained at a wavelength of 240 nm. The analytical curve from 5.0 to 100.0ppm of MDMA was obtained, showing a linear correlation coefficient of 0.9997 and a detection limit of 2.94ppm. This methodology was employed at the dosage of confiscated samples of ecstasy in the Scientific Police Laboratory of Ribeirão Preto-SP city.