Ядерная медицина и лучевая терапия

Dosimetric Comparison : Volumetric Modulated Arc Therapy (VMAT) and 3D Conformal Radiotherapy (3D-CRT) in High Grade Glioma Cancer-Cheikh Khalifa International Hospital Experience

Abstract

Imane. Benali, O.Kaanouch, H.Gouach, Z.Dahbi1, A.Naim, F.Kouhen

Background: Intensity Modulated Radiation Therapy (IMRT) is currently employed as a major arm of treatment in multiforme glioblastoma (GBM). The present study aimed to compare 3D-CRT with IMRT to assess tumor volume coverage and OAR sparing for treatment of malignant gliomas.

Materials and methods: We assessed 22 anonymized patients datasets with High Grade Glioblastoma who had undergone post operative Intensity Modulated Radiotherapy (IMRT) and 3D Conformal Radiotherapy (3D-CRT). This study will compare and contrast treatment plans Rapidarc and 3D-CRT to determine wich technique improves significantly dosimetric parameters.

Results: PPlans will be assessed by reviewing the coverage of the PTV using mean, maximum and minimum doses while the OAR doses will be compared using the maximal doses for each, as set out in the QUANTEC dose limits.

Conclusion: TThe use of IMRT seems a superior technique as compared to 3D-CRT for the treatment of malignant gliomas having the potential to increase dose to the PTV while sparing OARs optimally.