Сердечно-сосудистые заболевания и диагностика

Effect of Admission Hyperglycemia on Short Term Outcomes of Non-ST Elevation Myocardial Infarction

Abstract

Ali K

Aim: This study was undertaken to assess the impact of acute hyperglycemia (Admission Hyperglycemia) on short-term outcomes during hospitalization in patients with Non-ST elevation myocardial infarction (NSTEMI).

Patients and Methods: We analyzed 59 consecutive patients admitted for NSTEMI to the Coronary Care Unit of in Tishreen University Hospital. Patients were classified according to their admission blood glucose into two groups, the first group was admission hyperglycemia (defined ≥ 200 mg/dl), whereas the second group was without admission hyperglycemia, to assess its impact on In-hospital mortality and complications (Acute heart failure, Cardiogenic shock and Bleeding).

Results: In univariate analysis, in-hospital mortality was more prevalent in hyperglycemic individuals compared to non-hyperglycemic ones but without statistical significance (9.1% vs. 0%, p=0.07). In addition, patients with admission hyperglycemia developed acute heart failure (54.6% vs. 0%, p=0.0001) and cardiogenic shock (9.1% vs. 0%, p=0.0001) more than patients without admission hyperglycemia. In multivariate analysis, Admission Hyperglycemia was an independent risk factor for in-hospital mortality (OR: 2.3, 95% CI: 2-4.1, p=0.01) and acute heart failure (OR: 4.7, CI 95%:2.3-7.8, p=0.0001).

Conclusion: Admission hyperglycemia was an independent risk factor for in-hospital death and acute heart failure in STEMI patients.