Журнал эпилепсии

Exploring the Efficacy of Novel Antiepileptic Drugs: A Comparative Analysis of Recent Clinical Trials

Abstract

Mehar Chandra

Epilepsy, a chronic neurological disorder characterized by recurrent seizures, affects approximately 50 million people worldwide. While traditional antiepileptic drugs have made significant strides in managing this condition, there is an ongoing need for novel treatments that offer improved efficacy, fewer side effects and enhanced quality of life for patients. Recent advancements in drug development have led to the emergence of several new AEDs, which have been evaluated in recent clinical trials. Antiepileptic drugs are pivotal in managing epilepsy, a neurological disorder marked by recurrent seizures. Despite the efficacy of established AEDs, the search for new drugs continues due to limitations like insufficient efficacy in refractory cases, adverse side effects and individual variability in drug responses. The advent of novel AEDs reflects advances in our understanding of epilepsy's pathophysiology and pharmacology, aiming to offer improved outcomes.