Молекулярная и генетическая медицина

Gazing at The PubMed Reports on CRISPR Tools in Medical Research: A Text-Mining Study

Abstract

Singha DL and Sahu J

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat) system is one of the promising methods for targeted genome editing without interfering with intracellular mechanisms. This system is useful for treatment of various diseases and identification of genes responsible for those diseases. In the current study, we performed scientometric analysis along with text-mining of PubMed reports on CRISPR based research in medicine. The upshot of the study revealed cancer, tumour and inherited hereditary diseases as the most prominently studied diseases using the CRISPR tool. Here, we present the outcome of the analysis in the form of a brief systematic review on application of CRISPR tools in the field of medical research using network analysis emphasizing the mostly studied diseases. The review will definitely help the researchers working in the field of medical research to get an overall idea as well as shape their objectives.