Журнал цитологии и гистологии

Hypofractionated Stereotactic Radiotherapy for Orbital Metastases: A Case Report and Review of Literature

Abstract

Blerina Resuli, Roberto Lisi, Francesca De Felice, Daniela Musio and Vincenzo Tombolini

Objective: To evaluate the efficacy and clinical outcome of hypofractionated stereotactic radiotherapy (HSRT) in non-small-cell lung cancer (NSCLC) cancer patients with orbital metastasis.
Case report: A 61-year-old man was admitted to the hospital referring right ptosis and dry hacking cough. HSRT was performed for the orbital metastasis followed by chemotherapy with cisplatin (60 mg/m2) and pemetrexed (500 mg/m2) on day 1 every 21 days for 4 cycles and maintenance pemetrexed (500 mg/m2) on day 1 every 21 days. Control TC scan revealed a complete response of the orbital mass.
Conclusion: HSRT should be considered a valid therapeutic alternative in the management of selected patient with orbital metastases.