Неврологические расстройства

Idiopathic Inflammatory Myopathies Classification

Abstract

Tushar Trivedi

Discoveries of myositis-particular antibodies, transcriptomic signatures, and clinicoseropathological correlation guide type of idiopathic inflammatory myopathies (IIM) into 4 essential subgroups: dermatomyositis, immune-mediated necrotizing myopathy (IMNM), antisynthetase syndrome (ASS), and inclusion frame myositis (IBM) while leaving polymyositis as an ancient nonspecific prognosis of exclusion. This evaluate summarizes and feedback on latest information concerning the essential subgroup of IIM. Current IIM type calls for incorporated clinicoseropathological approaches. Additional information, consisting of transcriptomics, HLA haplotyping, and ability biomarkers assist tailoring categorization which can have destiny diagnostic and healing implications.