Журнал клинических случаев

Immunoglobulin D Multiple Myeloma-A Rare Case

Abstract

Sebnem Izmir Guner, Didem Karacetin and Ekrem Guner

Introduction Immunoglobulin D multiple myeloma (IgD MM) accounts for almost 2% of all myeloma cases and has usually an poor prognosis. Due to its rarity, the reports on this disorder in the literature are limited. Case Report We therefore present a case of Ig D multiple myeloma. The age of the patients was 56 years old and the common presenting symptoms were anorexia, weight loss and bone pain. The patient was also presented with neurological symptoms (peripherial neuropaty), renal impairment and kappa paraproteinemia. Conclusion The small group of patients who have IgD multiple myeloma is rare and considered to have a poor prognosis compared to other MM isotypes. The clinical features and prognosis of patients with IgD MM are not the same from those that characterize patients with other immunoglobulin MM subtypes. New treatment strategies that aim to induce high-quality responses before ASCT and after ASCT may be needed to improve the outcomes of such patients.