Журнал косметологии и трихологии

In Vitro Antifungal Screening of UPL-Pn-2 Peanut Seeds (Arachis hypogaea L.) Against Dandruff-Causing fungus, Malassezia Globosa

Abstract

Michael B. Bibon

This study aimed to screen the UPL-Pn-2 peanut seed extract for antifungal efficacy against dandruff-causing fungus, Malassezia globosa. Quantitative approach was conducted via in vitro antifungal screening through Kirby-Bauer test with experimental and control groups. Experimental group has 3 set-ups of peanut seed extract’s in varying concentrations ( 25%, 50% and 100%). For control group, 3 set-ups of commercialized tech grade boric acid were also prepared in different concentrations (25%, 50%, 100%). Discs with dried methanol were used for negative control set-up. ANOVA revealed that antifungal effectiveness of peanut seed extract varied with the concentrations, while t-test showed no significant difference between peanut extract vis-à-vis boric acid concentrations. Also, pure boric acid and peanut extract were more effective compared to lower concentrations. The screening revealed antifungal efficacy of UPL-Pn-2 peanut seeds against dandruff-causing fungus, Malassezia globosa, which shows promising results as organic alternative to commercialized anti-dandruff products.