Журнал клинических случаев

Infantile Exogenous Cushing Syndrome due to Misuse of Topical Corticosteroid

Abstract

Abolhassan Seyedzadeh

Background: Topical Corticosteroids have been ordered in Medical practice by many doctors for Various Skin diseases but prolong use of these Medication causes Systemic adverse effects including Cushing Syndrome. Iatrogenic Cushing Syndrome may occur with over use of potent topical steroids mostly due to Diaper dermatitis. Case report: We report a 3 month old female infant who developed Cushing Syndrome after diaper dermatitis treatment through misuse of Clobetasol without doctor’s Prescription. After diagnosis, the application of this topical corticosteroid was stopped and physiologic dose of prednisolon was prescribed to prevent an adrenal crisis for 2 months. Conclusions: Continuous use of moderate to high potency topical corticosteroids over several months can contribute to cushing’s syndrome. So parents must be informed by physicians about the adverse effect of steroids and they should be avoided in very young infant.