Журнал воспалительных заболеваний и расстройств кишечника

Intestinal Inflammation: Mechanisms, Implications and Therapeutic Approaches

Abstract

Renica Fizz*

Intestinal inflammation is a complex physiological response that plays a crucial role in various gastrointestinal disorders, including Inflammatory Bowel Disease (IBD). This abstract explores the mechanisms underlying intestinal inflammation, its implications for health and disease, and current therapeutic approaches. The keywords discussed in this abstract include intestinal inflammation, immune response, gut barrier dysfunction, inflammatory mediators, microbiota dysbiosis, and therapeutic interventions. Emerging evidence suggests that alterations in the gut microbiota composition, known as dysbiosis, can contribute to the development and perpetuation of intestinal inflammation. Dysbiosis disrupts the symbiotic relationship between the host and the gut microbiota, resulting in an imbalance of pro- and anti-inflammatory bacteria. The dysbiotic microbiota can activate immune cells, trigger inflammation, and contribute to the progression of intestinal diseases.