Раковая наука и терапия

Intracranial Hypertension Syndrome Revealing Cerebral Thrombophlebitis in a Patient treated for Breast Cancer by Tamoxifen after Chemotherapy

Abstract

Karima Oualla, Samia Arifi, Sihame Tizniti and Omar El Mesbahi

Cancer is a major risk factor for thromboembolic disease. This risk is increased by the therapies applied including hormone therapy. We report a case of a 54 years old patient, postmenopausal, treated for breast cancer who presented an intracranial hypertension syndrome 15 months after starting Tamoxifen. A brain scan with injection of contrast was performed and revealed a left lateral sinus thrombophlebitis extended to the ipsilateral jugular vein. Curative anticoagulation was started the same day of diagnosis with low molecular weight heparin. Symptoms were improved 5 days after starting anticoagulation.