Журнал клинических случаев

Laryngeal Chondrosarcoma: A Case Report

Abstract

Semmar A, Mouden K, El Allam O, El Majjaoui S, Kebdani T and Benjaafar N

Introduction: Laryngeal chondrosarcoma is a rare tumor. It mainly develops in cricoid cartilage, surgery is the treatment of choice. His prognosis is good. Case Report: A 55 year old man, non-smoking, was diagnosed with grade 2 laryngeal chondrosarcoma. Surgical treatment consisted of a total laryngectomy with bilateral neck dissection. Radiation therapy on the tumor bed was performed at a dose of 66 Gy in 33 fractions of 2 Gy once daily for 7 weeks. The follow-up of this patient is 12 months and his ECOG is 0. Discussion: Laryngeal chondrosarcoma is a rare tumor, It mainly develops in cricoid cartilage. It produces dyspnea, dysphagia, odynophagia, hoarseness, and airway obstruction. CT scan is the method of choice for studying the larynx. Endoscopy enables biopsy, which should be profound as the tumor develops at the submucosal. Histopathological examination showed immature chondrocytes with variable cytonuclear abnormalities. There are three grades of severity: Grade 1, 2, 3 of laryngeal chondrosarcomas. Surgery is the treatment of choice. Chondrosarcoma is considered poorly sensitive to radiation therapy. Chemotherapy has no role in this indication. Prognosis depends upon histologic grade and quality of exeresis. Conclusion: Laryngeal chondrosarcoma is a rare tumor, with slow growth and insidious clinical picture; Surgery is the treatment of choice, prognosis is generally good, and basically dependent on histologic grade.