Журнал клинических случаев

Neurobrucellosis with Gait Disturbance: A Neurological Case Report

Abstract

Soraya Mehrabi, Elahe shahriari, Motahareh Afrakhteh, Mitra Ranjbar, Marjan Zeinlai and Bahram Haghi Ashtiani *

Brucellosis is a multi-system infectious disease that exhibits various manifestations and complications. Neurobrucellosis is a rare but serious presentation of brucellosis that can be discovered in every stage of the disease. Laboratory tests, physical examination, and patient history are generally the basis for diagnosing the disease. It has both insidious and prolonged clinical course of the disease and long-term therapies. Also, the most common pattern of the exhibition is sub- acute or chronic. We reported a case of a young female who had a history of painless weakness in the right lower limb (proximal and distal) that started gradually and had progressed over time, and after a month she felt weakness in the left lower limb with the same pattern. Lumbosacral Magnetic Resonance Imaging (MRI) with and without contrast was shown evidence of enhancement thickening of caudal equina ventral roots. Brucella agglutination test was positive, the result was 1/160. And other clinical tests were normal. The patient was treated with Intravenous Injection (IV) Rifampicin and Intravenous Cotrimoxazole. The patient was discharged with good health and continuing all two medications for 5 months. The decision was taken to report this case as a result of the entire response in the patient’s illness after an enduring disease. Neurobrucellosis is a treatable disease in which it would be better to consider a high indication of suspicion. If ignored, it may cause significant morbidity and mortality