Журнал биомедицинских систем и новых технологий

Next-generation Sequencing Technologies and their Impact on Genomic Medicine

Abstract

Rebecca Michelson

Next-Generation Sequencing technologies have revolutionized genomic medicine, providing unprecedented insights into the genetic underpinnings of diseases and significantly enhancing our ability to diagnose, treat, and prevent a range of health conditions. By enabling rapid and cost-effective sequencing of entire genomes, exomes, and targeted regions, NGS has transformed the landscape of genomic research and clinical practice. The advent of NGS technologies marked a departure from traditional sequencing methods, such as Sanger sequencing, which were labor-intensive and costly. NGS platforms are capable of sequencing millions of DNA fragments simultaneously, allowing for the highthroughput analysis of genetic material. This capability has dramatically reduced the time and expense associated with sequencing, making it more accessible for both research and clinical applications