Журнал клинических случаев

Squamous Cell Carcinoma in Bladder Extrophy : A Case Report and Literature Review

Abstract

Asmae Touil, Hasnaa Loughlimi, Sarah El- Abbassi, Hafsa Elouazzani, Najat Mahassini, Hanane El- Kacemi, Kebdani Tayeb and Noureddine Benjaafar

Background: Bladder extrophy is a rare congenital anomaly, it is now well reconized that an exstrophy of the bladder is associated with an increased risk of bladder cancer.

Case presentation: We report the case of 34-year-old male with squamous cell carcinoma of an unreconstructed exstrophic bladder. Because of the locally advanced disease, he received neoadjuvant chemotherapy with favorable response. Then, he underwent a total cystectomy with uretero-intestinal anastamosis.

Results: The patient progressed three months after the surgery. Chemotherapy was established and he received 2 cycles, however, he died 2 months later.

Conclusion: Squamous cell carcinoma associated with bladder extrophy remains relatively high. These tumors tend to be aggressive, follow-up is mandatory in these cases.