Hadi Al-Hakami
Objectives: To evaluate the frequency of the thyroid gland invasion in patients with advanced laryngeal squamous cellcarcinoma submitted to total laryngectomy and thyroidectomy and to determine whether clinical and pathologicalcharacteristics of laryngeal carcinoma can predict glandular involvement. Methods: A retrospective case series with chart review, from March 2009 to January 2018, was undertaken in the Princess Norah Oncology Center, King Abdul-Aziz Medical City, Jeddah / KSA. An inception cohort of 56 patients with laryngeal squamous cell carcinoma was considered. Nine cases were excluded. All patients had advanced stage cancer larynx (clinically T3-T4) and underwent total laryngectomy in association with thyroidectomy. Total thyroidectomy was performed in all bilateral lesions or if there was suspicion of contralateral lobe involvement. Hemithyroidectomy was performed in all lateralized lesions. Retrospective histopathologic analysis of thyroid specimens was subsequently performed. The frequency of thyroid gland invasion was calculated and analysis of demographic, clinical and pathological characteristics associated with thyroid gland invasion was performed.
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