Журнал иммунобиологии

Theranostic Viral Nanoparticles for Autoimmune Diseases

Abstract

Yuste-Calvo C*, López-Santalla M, Garín M.I and Ponz F

Viral Nanoparticles (VNPs) as theranostic tools are a rapidly growing aspect of these particular types of nanoparticles. Among their multiple possible applications,
their contribution in the field of autoimmune diseases has recently emerged, since they can increase the sensitivity of detection of autoantibody levels significantly
allowing early diagnosis, prognosis and, consequently, the development of specific therapies. Based on the promising results obtained using nanoparticles derived
from Turnip Mosaic Virus (TuMV) in an animal model of Inflammatory Bowel Disease (IBD), this mini review discusses the possibilities of development of this VNP
as a power tool for diagnosis in immune-mediated diseases.