Журнал интегративной онкологии

Two Young Men with Leonine Facies and Generalized Itching - Two Case Reports of Sezary Syndrome

Abstract

Akter M, Khan MA, Afrose S, Ara T, Ferdous J and Islam MM

Two male aged 37 years and 29 years presented with generalized itching followed by thickening and reddening of whole body for 3 and 6 months respectively. On examination generalized erythroderma, lymphadenopathy and hepato-splenomegaly were found. In both cases leucocyte count was high and of which 80-90% were morphologically Sezary cells. Peripheral blood absolute CD4+ lymphocytes were very high in both the cases. Skin biopsy showed dense infiltrate of lymphocytes in the dermis with intraepidermal collection of lymphocytes. Bone marrow was infiltrated with Sezary cells.