Молекулярная биология: открытый доступ

Varied Profiles of Ricin-cell Interactions in the Pulmonary System after Intranasal Ricin Exposure

Abstract

Antoine Francoise

Intranasal exposure to ricin, a potent plant-derived toxin, leads to diverse interactions between ricin and pulmonary cells, impacting respiratory health and systemic toxicity. This review explores the multifaceted interactions of ricin with cells in the pulmonary system, encompassing mechanisms of uptake, intracellular trafficking, cytotoxic effects and immune responses. Understanding these interactions is crucial for developing effective therapeutic strategies and mitigating the harmful effects of ricin exposure on respiratory function and overall health.