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Журнал противомикробных средств

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Объем 9, Проблема 1 (2023)

Мини-обзор

Antimicrobial Drugs: A Lifeline against Infectious Diseases

Stephen De Silva

Antimicrobial drugs, including fluoroquiAntibiotics: Antibiotics are used to treat bacterial infections. They can be further classified into several categories, such as penicillin, cephalosporin, macrolides, tetracycline and fluoroquinolones. Each category has a unique mode of action and targets specific bacteria or bacterial components Inhibition of cell wall synthesis: Many antibiotics, such as penicillin and cephalosporin, interfere with the synthesis of bacterial cell walls. By disrupting this essential structure, the drugs weaken the bacteria, making them more susceptible to destruction by the immune system. Inhibition of protein synthesis: Certain antibiotics, like macrolides and tetracycline, inhibit bacterial protein synthesis. By blocking the production of vital bacterial proteins, these drugs impede bacterial growth and reproduction. Inhibition of nucleic acid synthesis: Antimicrobial drugs, including fluoroquinolones, interfere with the synthesis of bacterial DNA or RNA. This disruption prevents bacteria from multiplying and spreading, aiding in the eradication of the infection.

Мини-обзор

Understanding Anti-fungal Agents: A Closer Look at Their Mechanisms and Applications

Rosa Isla Anaya-Esparza

Echinocandins disrupt cell wall synthesis, weakening the fungal cell. Allylamines block ergo sterol production, hindering fungal growth. Combination therapy and emerging agents are also briefly mentioned. Consideration of potential side effects and drug interactions is essential. This abstract emphasizes the importance of anti-fungal agents in combating fungal infections and the ongoing research in this field to address the emergence of drug-resistant strains. These diseases are caused by fungi that can flourish in a variety of conditions and spread rapidly to people with weakened immune systems. Treatment plans have also become more challenging as a result of the rising incidence of drugresistant fungus strains and the increased usage of immunosuppressive medications.

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