Журнал клинических случаев

Journal of Clinical Case Reports (JCCR) successfully released issues with 108 abstracts. The submissions to the journal are subjected to peerreview process by the editorial board members or external subject experts. The complete editorial processing of the manuscript is done through the integrated online editorial manuscript submission and review system for greater transparency and faster article throughout. During 2019 around 100 articles were subjected to the peer-review process and all of those were accepted. In the volume 9 published during the year 2019, a total of articles were published (at an average of 7 articles per issue) of which, 70% articles were by foreign authors. A total of 236 research scientists from India and abroad reviewed the 108 articles published in volume 9. Average publication lag time of an article was further reduced to 6-8 months. I take this opportunity to acknowledge the contribution of Arnon Blum.

Even this high rate in the Mediterranean basin, multi-organ echinococcosis was exceptional. Outside typical hepatic involvement, malignancy was a first suggested diagnosis within extensive lesions. We report a rare case of a 74-year-old man suffering from hydatid disease mimicking spine and pulmonary metastasis

Dropped head syndrome occurs when the posterior musculature complex of the neck is weakened by different disorders, including Parkinson’s disease. We present a 48 year-old female patient visiting our clinic because of neck weakness and difficulty in maintaining her horizontal gaze. Her past medical history revealed a Parkinson’s disease discovered 6 months prior to admission, well controlled with oral medications. She then underwent a posterior cervical surgery including C2 to T3 instrumentation and correction in addition with C3 to C6 laminoplasty. After the operation, all radiological parameters returned to optimal values and the patient was satisfied with the result. Dropped head syndrome with failed conservative treatment can be successfully treated by surgical intervention with instrumentation from upper cervical to upper thoracic region and deformity correction.

46,XX testicular disorder of sex development is a rare cause of male infertility. There is a disagreement between the manifested sexual phenotype (male) and the genotype (female). It occurs in males with 46,XX karyotype who may have normal or ambiguous male genitalia, testosterone deficiency and infertility. With adequate hormonal treatment, the chance of having a good quality of life is high. In the diagnosis, the genetic study is fundamental for the identification of the gene that causes the disorder. The role of SRY gene is important because it allows classifying these males into two groups: those with SRY gene, which activates male sexual differentiation, translocated from Y chromosome to X (SRY-positive), and those without this translocation (SRY-negative). 80-90% of cases are SRY-positive. In the 1020% SRY-negative it is difficult to identify the gene responsible for the alteration. This would indicate the involvement of other genes linked to the X chromosome. This is a review of the first case of SRY-negative 46,XX testicular disorder of sex development with complete masculinization reported in Basque Country in which the cause of the disorder is being investigated, even without specifying. 

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