Журнал интервенционной и общей кардиологии

Earlier, in 2010-2011, our group of researchers proposed a New Theory of Cardiovascular Disease (CVD). According to this theory, many CVDs are caused by the malfunctioning of large arteriovenous anastomoses (AVA). Normally working AVA should open with a significant increase in blood pressure (BP) in order to ease pressure in the arteries and prevent damage to the walls of the arteries. But, on the other hand, AVA should be closed too on time, so that there are no significant losses of arterial blood and do not overload the venous pool.