Журнал тканевой науки и инженерии

Gliomas are the most common primary brain tumors, originating from glial cells in the central nervous system. These tumors exhibit significant heterogeneity, making their classification and treatment challenging. Gliomas can be benign or malignant, with the latter, known as glioblastoma, being the most aggressive and difficult to treat. This article provides a comprehensive overview of glioma cells, including their characteristics, classification, molecular features, and current advances in research and treatment strategies. By understanding the biology and behavior of glioma cells, researchers hope to develop more effective therapeutic interventions to improve patient outcomes.

Tissue integration, also known as osseointegration, is a crucial process in the field of biomaterials and tissue engineering. It involves the establishment of a functional and structural connection between an implanted biomaterial and the surrounding host tissues. Successful tissue integration is essential for the long-term stability and functionality of various biomedical applications, including orthopedic and dental implants, as well as tissue-engineered constructs. This article provides an in-depth exploration of tissue integration, discussing its significance, underlying mechanisms, factors influencing integration, and recent advancements in the field. Additionally, it highlights future perspectives and challenges, such as personalized medicine, immunomodulation, smart implants, and the integration of biological and synthetic materials, which will shape the future of tissue integration research.

Bone Mineral Density (BMD) is a critical indicator of skeletal health and plays a significant role in assessing the risk of osteoporosis and fractures. Understanding the importance of BMD and the factors influencing it is crucial for effective management and prevention of skeletal disorders. This review aims to provide an overview of the significance of BMD in evaluating bone health and the underlying factors that impact BMD measurements. Key determinants of BMD include age, gender, genetics, lifestyle factors (such as physical activity, diet, and smoking), hormonal status, and certain medical conditions and medications. Additionally, this review discusses the clinical relevance of BMD, its measurement techniques, and the interpretation of BMD results. The knowledge presented in this review emphasizes the significance of BMD assessment in identifying individuals at risk for osteoporosis and fractures, facilitating early intervention, and promoting strategies for maintaining optimal skeletal health.