Трансплантационные технологии и исследования

Adults following hematopoietic stem cell transplantation (HCT) frequently experience delirium; however, the clinical and neuroimaging correlates of post-HCT delirium have not been clearly defined. Therefore, using a retrospective cohort of 115 persons who underwent neuroimaging following allogeneic HCT, we investigated the prevalence of delirium and neuroimaging correlates of post-transplant delirium. Using previously approved techniques for the retrospective detection of post-procedural delirium assessed on the chart, delirium was determined. A multidisciplinary team with experience in HCT, psychiatry, and psychology independently reviewed the medical records of consecutive allogeneic HCT patients who had neuroimaging evaluations and transplantation at a single location between January 2009 and December 2016. Also noted were white matter damage and brain volume decrease neuroimaging indicators.

Hypervolemia frequently results in elevated cardiac output in patients with end-stage renal failure, particularly in those who are underdialyzed and those who have cardiac decompensation. This investigation looked at how kidney transplantation affected valvular heart conditions. 180 adult patients (n=180) who underwent kidney transplantation at the Division of Organ Transplantation, University of Debrecen, Hungary, between February 2015 and June 2018 were included in this retrospective data study. This investigation looked at the echocardiographic parameters and lab findings both before and after surgery (at 6 and 12 months). The Kruskal-Wallis analysis of variance test and 2/Fisher exact tests were used to conduct statistical studies. It was deemed important if P .05.

Frailty, a state of susceptibility and deterioration in function across several physiological bodily systems, is becoming recognised as a useful criterion to help clinicians forecast the likelihood of unfavourable outcomes in adult transplant candidates. The International Society for Heart Lung Transplantation proposes frailty testing in its listing criteria for heart transplantation from 2016. We set out to compile information on the value of frailty assessment in heart transplant candidates or recipients that has been published in the literature.