Журнал клинических исследований

Effects of Dietary-induced Weight Loss on Bone Marrow Fat Composition

Abstract

Daniel Gupta

The relationship between dietary-induced weight loss and bone marrow fat composition is a complex interplay that impacts both metabolic health and skeletal integrity. This comprehensive review synthesizes current literature to explore the effects of various dietary interventions on Bone Marrow Adipose Tissue (BMAT), encompassing changes in quantity, distribution, lipid composition and metabolic activity. Evidence suggests that while weight loss generally reduces total BMAT volume, qualitative shifts in BMAT dynamics and their implications for bone health are nuanced and multifactorial. Understanding these effects is crucial for optimizing weight loss strategies that preserve skeletal integrity amidst metabolic changes associated with obesity and caloric restriction.