Журнал нефрологии и терапии

Epidemiological Aspects of kidney Failure in Hospitalized Children in Brazil

Abstract

Cristina Malzoni Ferreira Mangia *,Andrade MC

Objective: The aim of this study is to evaluate the epidemiology, costs and outcome of children’s kidney failure in Brazil.
Methods: The study is an observational cohort study based in national govern database. Data were collected from all hospitals affiliated to Brazilian unified health system (SUS). We analyzed all children from neonatal period to 19 years old with diagnosis of renal failure based on the 10th revision of the International Classification of Diseases (ICD-10). Results: Demographic data were collected in eight cohorts from 1998 to 2007. There were 666.725 hospital admissions by kidney disease and 43,174 admissions by kidney failure. The mean of mortality rate, 4% in these cohorts. The admissions and mortality rate have been constant with high mortality under the age of 1 year since 1998. The incidence in boys was higher than in girls but was not significant (p > 0.05). The mean of length of stay was 9.55 days. The mean of annual costs was $5,075,641 million and $588 dollars per patient. In addition, the congenital malformations of the urinary system presented a coefficient of incidence in 1999 of the 0.08/1000 inhabitants or 4 fold less than 2005 (0.44/1000).
Conclusion: Kidney failure is a prevalent healthy problem that affects children from neonatal period to adolescence and presents high post natal mortality. Renal failure is associated to a large spectrum of different ethiologies and different levels of morbidity and consequent impact on the outcome. On account of this early diagnosis improvement and treatments would be established.