Разработка и применение биокерамики

Osteogenesis: The Science behind Bone Formation and Healing

Abstract

Zhang Yadong*

Osteogenesis, the process of bone formation and healing, is a complex and remarkable biological phenomenon. It encompasses the stages of intramembranous and endochondral ossification, which lead to the development of different types of bones in the body. Various factors, including genetic, hormonal, and environmental influences, play a crucial role in regulating bone formation. Additionally, the ability of bones to heal themselves after injury is a regenerative process involving stages of inflammation, soft callus formation, hard callus formation, and remodelling. Factors such as age, overall health, nutrition, and the type of fracture can affect the bone healing process. Advancements in osteogenesis research have led to innovative approaches, including stem cell therapy, growth factors, and biomechanics, to enhance bone regeneration and healing. This article provides an overview of osteogenesis, its influencing factors, and the fascinating ability of bones to heal, highlighting the importance of ongoing research in this field.