Журнал нефрологии и терапии

Renal Impairment and Cardiovascular Disease: Unraveling the Complex Relationship

Abstract

Sarah Deborah*

Renal impairment and cardiovascular disease often coexist and exhibit a complex interplay, leading to significant morbidity and mortality worldwide. This research paper aims to explore the intricate relationship between renal impairment and CVD, focusing on the underlying pathophysiological mechanisms, shared risk factors, and clinical implications. Understanding this relationship is crucial for early detection, risk stratification, and optimal management strategies to improve outcomes in affected individuals. Renal impairment and cardiovascular disease represent major public health challenges, with substantial overlap in their epidemiology and clinical manifestations. Chronic kidney disease is recognized as a potent risk factor for the development and progression of cardiovascular events, while CVD, particularly hypertension, atherosclerosis, and heart failure, significantly contributes to the progression of renal dysfunction. This paper aims to delve into the complex relationship between renal impairment and CVD, highlighting the underlying mechanisms and clinical implications.