Журнал нефрологии и терапии

Patients with advanced Chronic Heart Failure (CHF) are inclined to decrease renal capacity due to poor renal perfusion and abundance vasoconstriction. The intense administration of patients with decompensated CHF is frequently muddled by worry for precipitating deteriorating renal capacity. Despite the fact that diuretics and Angiotensin-Converting Enzyme Inhibitors (ACEIs) work on cardiovascular yield and for the most part work on renal perfusion in patients with decompensated CHF, a few patients have deteriorating of renal capacity. When aggravated renal dysfunction does occur, doses of ACEIs and diuretics are often reduced or with held in an attempt to preserve renal function. This training might be improper in patients with diligently raised filling tensions and low cardiovascular yield. Exasperated renal dysfunction may in this way drag out the intense therapy period of CHF, defer the help of indications, and result in imperfect dosing of ACEIs— specialists with portion subordinate long term good results in CHF.

Close urologic follow-up of renal transplant candidates and beneficiaries frequently uncovers prostate carcinoma at a beginning phase. Two patients who went through renal transplantation for end-stage illness additionally went through revolutionary perineal prostatectomy for limited prostate carcinoma, 3 years subsequent to uniting in 1 patient and 4 years prior to joining in the other. The perineal way to deal with prostatectomy might work with later renal transplantation and stay away from allograft harm.

???????????: ??????????????? (??) ? p-????????????? ( p- CS) — ??? ?????? ??????????? ???????, ??????? ?????????????? ? ????????? ? ????????????? ? ????????? ? ??????????? ???????? ????? (???). ??????????, ??? ??? ?????? ???????????? ????? ? ????????-?????????? ??????????? (???) ??? ? ?????????????????? ?????????????, ??? ? ? ??????? ?? ????????. ????????? ???????????? ???? ????????? ? ????? ???????? ????, ???????????? ?? ?? ? p- CS ????????-?????????? ????????????, ??????? ??????? ????? ????????-?????????? ??????? ? ?????????, ?????????? ?????????????? ?????? (??).

??????: ???? ????????? ?????????? ???????????? 119 ????????? ? ??. ???????????? IS ? p CS ?????????? ? ??????? ??????????????????????????? LC–????????? MS (UPLCMS/MS), ? ?????????????? ?????????, ????????? ? ????????-?????????? ??????, ?????????? ? ??????? ??????????????? ?????????????? ???????????. ??? ??????????? ????? ????? ???????????? ??????????? (IS ? p CS) ? ???????????? ????????? ???? ????????? ?????????? ? ??????????? ???????? ????????????? ??????. ??? ?????? ????????? ?????? (OR, 95% ????????????? ????????? (CI)) ?????????????? ??????????? ????????????????? ????????????? ????????????? ??????.

??????????: ????????? ??? ????????? ? ?? ???????? 20,10 (18,95, 22,90) ??/? ² . ????????? ???????????? ????????????? IS ? p CS ????????? 22,46 (13,45, 29,92) ??/? ? 12,41 (5,29, 24,45) ??/? ??????????????. ????????????? ???????? ?????????? ??????????? ????? ????????????? ????????????? IS ? ?????????????????? ??, ???????????, ?????????????, ????????, ??????? ? β2-??????????????? (β2-m) ? ??????????????? ????????????? ?????????? r ? ????????? p 0,22 (P = 0,020), 0,48 (P < 0,001), 0,32 (P < 0,001), 0,34 (P < 0,001), 0,28 (P = 0,002), 0,50 (P < 0,001). ????? ????????????? ????????????? ???????? ?????????? ??????????? ????? ?? ? ????????? ????????? ??????????? ?????????? (???) -0,46 (P<0,001). ????? ????, ???? ??????? ???????? ????????????? ?????????? ????? p CS ? ?????????? 0,32 (P<0,001).

??????: ???????????? ??????????? ??????? ???? ?????????? ????????-??????????? ????????? ????? ??? ????????? ??????? IS ? p CS, ??????? ???????????? ????????-?????????? ???????????? ? ????????? ?? ?????????????? ???????. ???????????? ?????????? ?????? ???? ????????? ? ??????? ??? ???????? ????????-???????????? ?????.

??????????? ? ????: ??????? ????? ???????? ?????? ??????????????? ????????????, ???????????? ??????????? ??? ???????????? ???????? ?????? ????????????? ???????????. ?????????? ??????????? ??????? ??????? ????? ???????? ?? ??? ??????? ?????????, ??????? ????? ???????? ?? ?????????? ????????? ???????????, ?????????? ??????? ?????? ???????. ?? ??????? ?????? ?? ????????? ????????, ???????????? ?? ?????? ??????? ?????????? ???????? ??????????? ???????? ??????? ????? ??? ?????????? ????????????????? ???????????? ???????? ?? ?????. ????? ????, ?????? ????? ??? ????????? ?? ???????? ??????? ????????? ?????????? ?? ??????? ????????????.

??????: ?? ???????? ??? ??????????? ??????? ??????????? ?????, ??????????? ? ?????? ? 1 ?????? 2017 ???? ?? 31 ??????? 2020 ????. ?? ????????? ??????? ????????????????? ????? ?? ????? ????????????. ?????? ?????????? ?????????????? ? ????????: ??????, ????????? ? ?????????, ??????, ????????? ? ??????????, ? ??????, ????????? ? ???????????? ???????. ??????? ???????? ??????????, ???? ??? ???????? ??????????? ???? ?????????? ?? ????? ?????? ?????????, ? ??? ??????????????????? — ?? ????? ?????? ???????? ? ?????? ???????? ??? ??????????? ???????????. ???????, ?? ??????????????? ?????????????? ?????????, ????????? ?????????????.

??????????: ?? 82 ?????????? ??????? ????? 35 ??????? (43%) ???? ???????????, ? ????????? 47 ??????? (57%) ???? ?????????????. ??? ????????? ?????????? ? ???????????? ????? ?? ??????????, ??? ???????, ???, ???, ???, ????????, ?????? ????, ?????????? ???????? ? ?????????? ?????? ???? ??????????? ? ????? ???????.

??????????: ???? ???????????? ????????????? ??????? ??????? ???????????? ???????? ??????? ?????, ????????? ? ??????????? ????????????????? ???????????? ???????? ?? ?????. ???????, ???, ???, ???, ????????, ?????? ????, ?????????? ???????? ? ?????????? ?????? ?? ?????? ?? ??????? ????????????. ????????? ?????? ??????? ???????? ???????????? ????? ????????????.

?????????????? ????? ???????????? ????? ????? ????????? ? ?????, ????? ??? ??????????? ??????? ???????????? ?????? ???????? ????????. ???????? ?????, ????????????? ??????????? ????????, ??????? ????????????????, ???????? ? ?????????, ? ????? ?????????? ??????????? ????????? ?????????? ???????????? ??????? ???????? ???????? ? ?????. ????? ????, ? ????? ????? ??????? ?????????? ? ???????? ????????? ?????? ??????? ????? ?? ????????? ?? ????????? ? ????????????? ???????? ?????????. ????????? ??????????? ? ????????? ? ?????????????? ????????? ???????? ?????? ?? ??? ????? ??????????????. ??? ?? ?? ?? ????, ????????????? ? ????? ?????????? ???????? ??? ??????.