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Журнал нефрологии и терапии

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Объем 7, Проблема 4 (2017)

исследовательская статья

Ochratoxin A Detection by HPLC-FL in Processed Baby Foods

Bonerba E ,Ceci E *,Balzaretti C ,Vallone L ,Crescenzo G ,Di Pinto A ,Celano GV ,Tantillo G ,Bozzo G

270 samples of different types of pasta and cereal products, distributed in a nursery school canteen in Milan (Italy), were analyzed to estimate the occurrence of ochratoxin A. OTA was found in all analyzed samples (100%), 39 samples exceeded the maximum limit established by European Commission Regulation for OTA in the foodstuffs listed in the relevant category. The mean concentration of ochratoxin A in samples of pasta, intended for children (over 5 months) consumption was 0.56 μg/kg; the mean concentration in organic pasta was 0.91 μg/kg and the mean concentration detected in cereal products was 3.12 μg/kg. Considering that in European Countries wheat products are the first solid food eaten by babies from the earliest stages of weaning and in the light of the multiple and repeated international food alert notification on OTA occurrence in cereals and cereals product, surveillance should be continuous for an effective risk assessment, especially in these vulnerable groups of consumers.

исследовательская статья

Relationship Between Asymmetric Dimethylarginine (ADMA) and Atherosclerosis in Chronic Renal Failure Patients

Alsayed Rashed ,Kamel Soliman ,Abdelaziz Aun ,Haitham Ezzat *

Background: Serum ADMA level was high in hemodialysis patients as compared to healthy control population. Increase in ADMA levels may play a role in atherosclerosis dependent morbidity and mortality. Objective: Assessment of the relationship between serum ADMA and atherosclerosis. Patient and methods: Serum ADMA was measured using ADMA ELISA Kit; atherosclerosis was assessed by non- invasive methods including FMD and CIMT in 3 groups (50 ESRD patients undergoing hemodialysis, 25 CKD patients stage IV and 25 healthy control subjects). Results: CKD and ESRD patients on regular haemodialysis have significantly greater ADMA, CIMT and lesser FMD than do control subjects with normal renal function. Both groups of patients have higher cholesterol and triglycerides levels than do control subjects which could be related to serum ADMA. Serum albumin was reduced in haemodialysis and CKD patients; it has an inverse correlation with serum ADMA. Conclusion: Patients of CKD and haemodialysis have earlier endothelial dysfunction than do control group and this explains why they have higher incidence of cardiovascular morbidity and mortality. Integration of ADMA into currently applied risk scores still needs to be validated.

исследовательская статья

Нарушения сна у пациентов, находящихся на гемодиализе: имеет ли значение РКФ?

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???????????: ???????????? ??? ?????????????? ??? ???. ?????????? ??????? ????? ?????? ???????????? ????? ? ????? ????????? ???????? ? ???????????? ????????? ?? ???????. ???????? ??? ? ????????? ?? ?????????????? ??????? ?????? ????????, ?? ?????? ????????? ???????????? ??????? ??? ? ????????? ?? ???????????. ??????: ???? ???????????? ???? ?????????? ?? ?????? ??????????? ??? ? ????????? ?? ??????????? ? ??????? ?? ??? ?????????? ??????? ?????. ???? ????????? ?????????? ???????????? 80 ????????? ?? ??, ??????? ???? ????????? ?? 2 ??????. ?????? I ???????? 30 ????????? ?? ?? ? ???, ? ?????? II ???????? 50 ????????? ?? ?? ??? ???. ??? (Kru) ???????????? ? ??????? ?????????: ???????????? ????? ???? x ???????????? ???????? ? ????/???????????? ??????/??????? ??????? ????? ????????. ??? ??????? ??????? ????? ???????? = (??? 1 + ??? 2)/2. ??? 1 ???????? ????? ??????? ??????? ??????, ? ??? 2 ???????? ????? ?????? ???????? ??????. ???? ????????? ??????????? ???????? ???????????? ????????????. ?? ??????? ????????? ????????? ??? ? ????? ???????: ?????????? ????? ?????? ??????? ??????????, ??????? ??????????? ??? ????? ????????????? ?????? ?? ???????? ???????? ??????????? ??? (IRLSSG) ? ?????????? ??????? ?????????? ????? ??????????? ?????? ????? ?????????? ???????. ??????????: ? ?????? I 43,3% ???? ????????? ? 56,7% ????????? ?? ??????? ????????? 40,47 ± 13,96 ??? ? ??????? ?????????????????? ??????? 4,38 ± 2,86 ???. ? ?????? II 38% ???? ????????? ? 62% ????????? ?? ??????? ????????? 54,68 ± 9,36 ??? ? ??????? ?????????????????? ??????? 6,90 ± 3,82 ????. ????? ?????? ???????? ??????????? ?????? ???????????? ??????? ? ???????? ? ????????????????? ??????? (p = 0,000, 0,002 ??????????????). ????? ????? ???????? ??????????? ?????? ???????? ??????? ? ????????? iPTH (106,71 ± 57,34 ??/??, 175,36 ± 15,71 ??/??, p=0,000). ?????????????????? ?????????? ????????? 62%, ?? ??? ????????? IRLS 18,7% ? EDS 12,5%. ?? ???? ????????????? ???????? ??????? ????? ??????? I ? ??????? II ? ????????? ??????? ??????? ??????????, ? ?? ????? ??? ????? ???? ???? ????????????? ???????? ??????? ? ????????? ?????????????? ???????? ??????????? ??????????? ? ?????????? ??????? (p=0,040, 0,004 ??????????????). ?? ???? ???????? ?????????? ????? Kru ? ????? ?????? ??????? ??????? ??????????, ????? ?????? ???????? ??????????? ? ????? ?????? ????? ?????????? ???????. ? ????? ???????????? ??????????? ????????????? ?????????? ????? Phosph ? ????? ?????? ???????? ??????????? (p=0,010). ????? ??????? iPHT ???????????? ? ????? ?????? ???????? ??????????? ? ????? ?????? ????? ?????????? ??????? (p=0,027, 0,038 ??????????????). ??????????: ????????? ??? ???????? ?????????????? ? ????????? ? HD. ???????? ? ??????? ??????? iPTH ? ??????? ????? ??????? ???? ????????? ???. ?????????? ??????? ????? ????? ????? ??? ???????? ?????? Ca, ??????? ? iPTH, ?? ?? ??????? ?? ????????? ??? ?? ???????? ? ????? ????????????.

История болезни

Летальный исход у ребенка с поздней диагностикой заднего уретрального клапана в стране с низким уровнем дохода: описание случая и выводы

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????????: ??? ???????????? ? ??????? ?????????? ????????????? ????? ? ????????? ?????????? ????????? ??????????????? ????????????, ????? ????????? ?????? ???????? ????????????? ?????. ??????? ??????????? ????? ????????? ????? ???????? ? ????????? ???????????. ???????? ??????: ?? ???????? ????????????? ???????? ???????? ????, ????????????? ?? ?????? ??????? ??????? ??????????? ????? (???) ? ???????????. ? ???? ? ???????? ???? ???????????? ???????? ????????????? ?????. ??? ??????? ???: ?????? ??????????? ????? ? ??????????, ????????? ? ?????? ??????????? ????????. ?????????????? ??????? ???????? ??????????? ???????? ??????? ????????, ??????? ?????????? ??? ? ???????????? ??? ?????????? ?????????? ????????????? ????? ????? ???????? ???????. ? ?????????, ?? ???????? ???????? ?? 3-? ???? ????? ???????? ??-?? ??????? ???????????? ????????????? ? ???????????? ????????. ??????????: ???? ?????? ????????? ?????? ? ??????? ? ?????? ??????? ?????? ?????? ????????? ??????? ??????? ???????? ????????????? ?????, ????? ???????????? ? ????????? ? ???????????? ????????? ????????????? ?????.

исследовательская статья

Прерывистый гемодиализ низкой интенсивности против гемодиафильтрации on line у ​​пациентов в критическом состоянии с сепсисом и острым повреждением почек. Выбор лучшего лечения в развивающейся стране

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????????: ?????? ??????????? ????? ???????? ????????? ???????????? ? ????????????? ????????? ? ????????, ? ???????? ?????????????????? ?????????? ????? 10% ? ????? ??????? ??????? ????????????????????? ??????????. ??? ???????????? ?????????????? ???????? ??????? ????? ?????? ??????????? ? ???????, ??? ???? ????????? ????????? ???????. ?? ?????? ????????????? ???????? ??? ???? ????????? ?????????? ??????????? ???????. ????: ????? ???????????? ???? ?????????????????? ???????????? ??????? ? ??????? ??????-????????????????? (??????????? ?????) ?? ????????? ? ??????????? ???????????? ??????? ????????? ?????? ????????????? ? ????????? ? ???????? ? ?????? ???????????? ?????. ?????????? ???????????? ???????????? ????: ??????????, ???????????? ?????????, ??????????? ?? ????????????? ?????????? ?????? ? ??????????? ? ????????? ??????????? ???????. ??????????: ????????? ? ????????????? ???????????? ? ????????? ? ???????? ? ?????? ???????????? ?????. ??? ?????? ????????? ??????? ? ??????? ???????????? ??????????? ??????? ????????? ?????? ????????????? (?????? A: n 35) ?? ????????? ? ??????-?????????????????? (?????? B: n 30). ????? ??????????? ????????? 49,2% (?????? A: 60% ?????? ?????? B: 36,6% p=0,061). ??????? APACHE 2 ? SOFA ? ????? ??????? ???? ????? (p=0,26 ? 0,98 ??????????????). ????? ?????????? ? ????????? ??????????? ??????? (GA: 16,7; GB: 9,9 p=0,044), ??????????? ?? ???????????? ?????????? (GA: 9; GB: 4,1 p=0,084), ??????????? ?? ????????????? ?????????? ?????? (GA: 11,2; GB: 6,5 p=0,12). ??????????: ??????-????????????????? ???????? ????????????? ???????? ???????????? ??? ?????????? ? ????????? ??????????? ???????, ?? ????????? ? ????????????? ???????????, ??????????? ?? ????????????? ?????????? ?????? ???????? ????????????, ?? ?? ???? ?????????. ?????????? ?? ???? ????????????? ????????. ?????????? ???????? ???????????? ??????-????????????????? ? ????? ??????????? ?????? ? ????????? ? ??????????? ????????? ? ????????.

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