Журнал генетики и исследований ДНК

CORONAVIRUS & COVID-19

Abstract

Senanur Uslu

Coronaviruses are a large family of viruses known to cause more serious diseases from the common cold, such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). Coronaviruses were identified in the mid-1960s. Sars-Corona Virus (SARS-CoV) is a coronavirus that was first seen in China in February 2003 and causes severe acute respiratory failure. As the largest known RNA viruses (because coronaviruses have the largest genome of RNA viruses), CoVs are further divided into four types: alpha coronavirus (α-CoV), beta coronavirus (β-CoV), gamma coronavirus (γ-CoV), and delta coronavirus (δ-CoV); the first two only infect mammals, including bats, pigs, cats and humans. Gamma coronavirus mostly infects birds and Delta coronavirus can infect both birds and mammals. This novel coronavirus is now the seventh member of the Coronaries, which is known to infect humans. All Coronaviruses belong to a genus. All of these geniuses are in the Coronaries family, making up one of the two subfamilies. Coronavirus, Nidovirales, which causes infections mainly in the respiratory and gastrointestinal tract, belongs to the Orthocoronavirinae subfamily, respectively in the Coronaviridae family. Previously, with serological analysis, the differences in the Coronavirus species used were understood and the Coronaviridae family was examined by dividing it into 4 antigenic groups.

But then, by examining the monoclonol antibody analysis and nucleotide sequences in the species and divisio groups, the classification was reduced to 3 antitigenic groups.