Журнал инфекционных болезней и медицины

Patients with Tick-borne Encephalitis and Co-infections: Proteomic Profile of their Plasma

Abstract

Tomasz Rogalska

Tick-borne Encephalitis (TBE) is a significant viral infection transmitted by tick bites, leading to severe neurological complications. Co-infections with other tick-borne pathogens, such as Borrelia burgdorferi, the causative agent of Lyme disease, complicate the clinical presentation and management of TBE. Proteomics, the large-scale study of proteins, offers insights into the pathophysiological mechanisms and potential biomarkers for diagnosis and treatment. This article investigates the proteomic profile of plasma in patients with TBE and co-infections, aiming to elucidate the complex interactions between multiple pathogens and the host's immune response. We discuss current findings, challenges, and future directions in this emerging field.